Yako's father was murdered in a locked room. She then meets a man named Neuro Nougami who is a demon from Hell who eats "riddles." He forces Yako to act as a detective so he can solve mysteries. Neuro longs to eat the ultimate mystery.

Majin Tantei Nogami Neuro:

• 1. Food
• 2. Community
• 3. Laughing
• 4. Dog
• 5. Rental
• 6. Hair
• 7. Box
• 8. Dream
• 9. Tightening
• 10. One [Alone]
• 11. Light
• 12. Image
• 13. X
• 14. Trip [Dreamy Feeling]
• 15. Dragon
• 16. Spring
• 17. Pursue
• 18. Key
• 19. 2 [Pair]
• 20. Desk [Woman]
• 21. Arrange [Tail]
• 22. Woman [Witch]
• 23. Blame
• 24. Dice
• 25. The Most